All three spice blends fall under the same category with standard base ingredients, like paprika, pepper, garlic, and onion powder.

However, Cajun Seasoning tends to be the spiciest, while Creole seasoning often has a variety of herbs mixed in.

When in doubt, go with Blackened Seasoning, a spice blend that tends to fall directly in the middle.” And of course blackened is considered a method. So you could use any of the 3 spice blends depending on your heat preference. You just want to blacken the fish. otherwise its just cajun fish.